The BAU helps Rossi's daughter Joy look into the disappearance of a Virginia college student. Also, the team is alarmed when Giuseppe Montolo dies in prison after warning Morgan about the Dirty Dozen hitman ring, JJ returns from maternity leave, and Reid becomes concerned for the well-being of his mother.
- Lea Coco - Sam Burnett
- Sameera Eligeti - Aasia Desai
- Jess Gabor - Paddy Morris
- Jordan Hendricks - Nerd #1
- Stephen Hershey - Peter Booth
- Robert L. Hughes - Paul Larson
- Tasie Lawrence - Bahni Desai
- Kyra Locke - Allison
- Robert Neary - Giuseppe Montolo
- Leif Steinert - Tom Larson
- Amber Stevens - Joy Struthers
- Aaron Hotchner: "We are all sharks, circling, and waiting for traces of blood to appear in the water." — Alan Clark
- David Rossi: "To a father, nothing is dearer than a daughter." — Euripides
- Credited as "Reporter"