- Cynthia Rose Hall - Guard
- Calvin Harrison - Agent Cal
- Richard T. Jones - Officer Lionel Wilkins
- Jane Lynch - Diana Reid
- Gia Mantegna - Lindsey Vaughn
- Shemar Moore - Derek Morgan
- Aubrey Plaza - Cat Adams
- Ellington Ratliff - Ronnie Hawks
- Beth Riesgraf - Maeve Donovan
- Kevin Will - John Fords
- "Moonlight Serenade" by Glenn Miller and His Orchestra
- "Journey On" by Elms District
- Emily Prentiss: "The villainy you teach me I will execute, and it shall go hard, but I will better the instruction." - William Shakespeare
- The term "red light" is used both as a noun (a red traffic light instructing vehicles to stop moving) and as a verb (to refuse an action).
- A scene from the Season Eight finale episode "The Replicator" is reused. In it, two helicopters used by the BAU are flying overhead the rooftops.
- In the end scene of Episode 22 when the spike strips are deployed, 2 newer model Chevy SUVs were shown, but when they get hit by the semi they are older models.
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