The BAU travels to New Jersey where several people have been poisoned with LSD ten times more potent than the street version. They realize that it was only a test run and that the unsub is planning a larger attack.
- Matt T. Baker - Danny Wallace
- Jon Barton - SWAT Leader
- James Bartz - Brian Devons
- Bill Doyle - Uniform Officer
- James Howell - Desk Sergeant
- Sonia Jackson - Head Nurse
- Nick Jameson - Edward Hill
- Braeden Lemasters - Eric Fisher
- Peter MacKenzie - Jack Fisher
- P. David Miller - Trooper
- Fred Ochs - Doctor
- Lynn Odell - Lynn Dempsey
- Annie Quinn - Samantha DiForio
- Nestor Serrano - Detective Hanover
- Jayne Taini - Nell Trucco
- Suzanne Whang - Herself
- Amy Wieczorek - Janice
- "Rockethouse" by Rockethouse
- "Club Foot" by Kasabian
- "Wishful Thinking" by Wilco
- "Don't Go Tellin' The Whole World" by Gus Black
- Jason Gideon: Roman philosopher Lucretius said, "What is food to one, is to others bitter poison."
- Jason Gideon: Confucius warned us, "Before you embark on a journey of revenge, dig two graves."