Disambiguation: This page is about the episode. For the person, see Luke Alvez
- Daniella Alonso - Doctor Lisa Douglas
- Sean Bolger - Randy Cooper
- Chad Guerrero - Eduardo Ramos
- Teresa Huang - Medical Examiner Weiss
- Hemky Madera - Inspector Manny Silva
- Kalea McNeill - D.C. Metro Cop
- Johnny Messner - Jeremy Grant
- Corey Reynolds - Phil Brooks
- Tim Stafford - Paul McEntee
- Michael Teh - Ken Ronson
- Javon Terrell - Mike Everson
- Luke Alvez: "I'm a fighter. I believe in the eye-for-an-eye business." — Muhammad Ali
- This is the fifth episode in which a main character's first name is used as the title, the first being the Season Three episode "Penelope," the second being the Season Six episode "J.J.," the third being the Season Eleven episode "Derek," and the fourth being the Season Twelve episode "Spencer."
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