A serial killer eludes Gideon and the BAU by changing his appearance like a chameleon. They track the killer across the south but have to look beyond his multiple appearances and profile the man underneath in order to locate him, before he takes his next victim.
- Jon Barton - SWAT Leader
- Yara Brighton - Murder Victim
- Michael W. Catlin - Hank Bloomberg
- Andy Comeau - Mark Gregory
- Meegan Godfrey - Nicole Wegener
- Brian Groh - Motel Clerk
- Joey Honsa - Kelly Dalton
- Robert Lee - Ted Bundy
- Sathya Jesudasson - Motel Manager
- DaJuan Johnson - Oscar
- Trary Maddalone - Jenna Alban
- Robert Pine - Doug Gregory
- Mark Totty - Agent Raymond McCarthy
- Eltony Williams - Agent #1
- Alicia Ziegler - Allyson Glennon
- Jason Gideon: The French philosopher Voltaire wrote, "There are some that only employ words for the purpose of disguising their thoughts."
- Jason Gideon: The author François de la Rochefoucauld wrote, "We are so accustomed to disguise ourselves to others that in the end we become disguised to ourselves."
- Credited as "Room Service"